Specialized instruments measure numerous physical parameters before and after product use. These include surface topography, elasticity, firmness, hydration, barrier function, sebum, and color/complexion. The result is numerical data that can be tracked over time, compared across formulations, and evaluated with regard to the intricacies of skin composition.
You may be screening prototype formulations or preparing to launch a finished product with performance claims. Either way, bioinstrumentation provides measurable evidence of what your product does on and to skin. CPT℠ Labs pairs a wide range of state-of-the-art bioinstrumentation with current testing methodologies to evaluate the parameters most relevant to your formulation and your claims.
Anti-aging and complexion claims depend on precise measurement of changes at the skin’s surface. CPT℠ Labs employs complementary imaging systems to capture and quantify those changes.
The Aeva-3D-HE uses fringe projection and stereovision, also known as active stereometry, to combine a wide field of view with high resolution. That flexibility supports a broad range of study designs, from wrinkle reduction to body reshaping. It delivers quantitative efficacy assessments for cosmetics, spa and dermatological procedures and other topical formulas.
PRIMOS™ image analysis produces high-quality 3-D imagery of skin texture and surface topography. This data informs product development and supports anti-aging claims such as “reduces the appearance of fine lines and wrinkles.”
The Visia-CR™ captures images under multiple lighting conditions and adds PRIMOS™ 3-D capture for combined complexion and surface topography analysis. Computerized data analysis can then support claims such as “lightens the appearance of dark spots” and “reduces the appearance of dark circles, fine lines, and wrinkles around the eyes.”
Each lighting mode isolates a different set of skin features, from surface texture and wrinkles to sub-surface pigmentation and porphyrins. This allows each parameter to be visualized and analyzed on its own.





















CPT℠ Labs measures changes in skin moisturization using specialized instruments, including the Corneometer and MoistureMeterSC. This testing is essential for evaluating the efficacy of moisturizers and other skin care products and for substantiating moisturization claims.
Our clinical bioinstrumentation staff use a Vapometer to measure TEWL, a key indicator of skin barrier function. TEWL data shows whether a product breaks down, repairs, or enhances the skin’s natural barrier. That information is relevant to both safety and efficacy.
The D-Squame™ technique provides detailed insight into skin dryness and exfoliation. It guides product development to address these concerns and supports skin moisturization and exfoliation claims.
Changes in the skin’s viscoelastic properties directly measure product performance. Using instruments such as the Cutometer and Elastometer, CPT℠ Labs quantifies elasticity and firmness after use of cosmetic formulations. This data supports both formulation development and claim substantiation.
Measuring changes in sebum on the skin supports sebum production and reduction claims. It also provides valuable direction when formulating for specific skin types, including acne-prone skin.
HairMetrix uses the VisioMed D200 for global image capture with real-time analysis. Its AI-driven software analyzes unclipped trichoscopy images for general hair counts. With clipped-hair imaging, it determines anagen/telogen ratio and produces more accurate hair count data. Compare mode places baseline and follow-up images side by side to demonstrate progress over the course of treatment.
Please note, any and all claims and the substantiation of those claims are the responsibility of the study sponsor.
Claim Category | Example Claim Language | Method(s) |
Fine lines & wrinkles | “Reduces the appearance of fine lines and wrinkles” | PRIMOS™, Visia-CR™, Aeva-3D-HE |
Complexion & dark spots | “Lightens the appearance of dark spots” | Visia-CR™ |
Eye area | “Reduces the appearance of dark circles” | Visia-CR™ with PRIMOS™ |
Firmness & elasticity | “Visibly firmer skin” | Cutometer, Elastometer |
Moisturization | “Hydrates skin for up to [X] hours” | Corneometer, MoistureMeterSC, D-Squame™ |
Barrier function | “Supports the skin’s natural barrier” | Vapometer (TEWL) |
Dryness & exfoliation | “Reduces visible flaking” | D-Squame™ |
Oil control | “Reduces surface oil” | Sebum measurement |
Body contouring | “Visibly reshapes” | Aeva-3D-HE with Visio 4-D Bench |
Hair density | “Visibly fuller hair” | HairMetrix |
Our Clinical Bioinstrumentation Laboratory is equipped with a wide range of state-of-the-art instruments. It is operated by a well-seasoned staff using the most current testing methodologies. We are ready to test your cosmetic formulations in support of product development, efficacy determination, and claim substantiation.
Contact us to discuss your next clinical bioinstrumentation study.